Ontario Registered Pharmacy Technician (RphT) Practice Exam

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Dextrose 25% 1000mL is ordered. On hand is Dextrose 70% solution. How much of the 70% Dextrose solution and sterile water will be used to fill this order?

  1. 250mL Dextrose 70% and 750mL of sterile water

  2. 357mL Dextrose 70% and 643mL of sterile water

  3. 424mL Dextrose 70% and 576mL of sterile water

  4. None of the above

The correct answer is: 357mL Dextrose 70% and 643mL of sterile water

Explanation In order to fill the order for Dextrose 25% 1000mL, we need to dilute the Dextrose 70% solution to a lower concentration. According to the concentration and volume equations (C1V1 = C2V2), we can determine that we need 357mL of the 70% solution and 643mL of sterile water to create 1000mL of Dextrose 25%. Option A is incorrect because 750mL of sterile water is not enough to reach a 25% concentration, while option C is incorrect because it uses too much Dextrose 70%. Option D is incorrect because there is a correct combination (option B) that can be used to create Dextrose 25% 1000mL.

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