Ontario Registered Pharmacy Technician (RphT) Practice Exam

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Gentamicin injection is normally given to a patient at 5mg/kg/day divided into 3 doses. If a patient weighs 164lbs what is the approximate strength per dose for that patient?

  1. 25mg

  2. 75mg

  3. 124mg

  4. 142mg

The correct answer is: 124mg

An incorrect answer could be D. While D may seem like a close approximation, it is actually too high. If we multiply 164lbs by 5mg/kg, we get 820mg. Then, dividing this by 3 doses, we get approximately 273.3mg per dose. D is significantly higher than this amount. An alternative explanation could be: A common rule of thumb for weight-based dosing is to convert the weight from lbs to kg by dividing by 2.2. In this case, 164lbs ÷ 2.2 = 74.5kg. Multiplying this by 5mg/kg, we get a total of 372.5mg for the entire day. Dividing this by 3 doses, we get approximately 124.2mg per dose, which is closest to option C. This method ensures that the

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