Ontario Registered Pharmacy Technician (RphT) Practice Exam

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Why are antidepressants often associated with non-adherence?

Adverse effects may be difficult for patients
Patients mistrust of psychiatrists
They are usually taken multiple times a day
All the above

The correct answer is: Adverse effects may be difficult for patients

Adverse effects such as nausea, weight gain, and sexual dysfunction are common side effects of taking antidepressants which can make it challenging for a patient to adhere to their medication regimen. This often leads to patients discontinuing or not taking their medication as prescribed. While B and C may contribute to non-adherence in some cases, they are not the main reason why antidepressants are often associated with non-adherence.